Database Overview

The database currently contains 474 plastic-degrading enzymes from diverse microorganisms that have been reported in the scientific literature for their plastic biodegradation capabilities. These enzymes target 34 different types of plastic polymers, with detailed characterization data including 3D structures, phylogenetic relationships...

PlaszymeDB is updated regularly to incorporate new discoveries and research findings in the rapidly evolving field of plastic biodegradation. The database serves as a central resource for researchers working on plastic pollution solutions, enzyme engineering, and environmental biotechnology applications.

Database Features

PlaszymeDB provides several options for exploring and utilizing the curated enzyme data:

• 🔍 Search and browse enzymes by name, EC number, plastic type, or host organism with advanced filtering capabilities
• 🧬 Access detailed enzyme information including sequences, structures, and biochemical properties
• 🔬 Perform BLAST searches to identify similar sequences in the curated database
• 🌳 Explore evolutionary relationships through interactive phylogenetic trees powered by iTOL
• 📊 View comprehensive statistics and visualizations of enzyme distribution and properties
• 💾 Download sequence data and metadata in standard formats for further analysis

Data Sources and Quality

The enzyme items in PlaszymeDB have mainly been integrated and collected from within the degradation enzyme databases (such as PMBD, PlasticDB, PAZY), and have undergone comparison and verification with biological databases (such as UniProt, NCBI and PDB). Each entry contains diverse information and is internally displayed.

The database maintains strict quality control standards, with regular validation of sequence data, structural information, and literature references. Cross-references to external databases ensure data consistency and provide users with access to additional resources and information.

Citation

If you use PlaszymeDB in your research, please cite our work. A peer-reviewed publication describing the database is currently in preparation and will be made available upon acceptance.

Contributing to PlaszymeDB

We welcome contributions from the scientific community to improve and expand the database. If you have information about plastic-degrading enzymes that could enhance our collection, or if you notice any errors or omissions, please contact us with your suggestions.

We actively monitor the literature for new discoveries and appreciate notifications about recent publications or newly characterized enzymes that should be included in future database updates.

Contact Information

For questions, suggestions, or collaboration inquiries, please reach out to our team: